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JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice  infected with SARS-CoV-2 develop severe and fatal respiratory disease
JCI Insight - Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

Biotechnology - hACE2 transgenic mouse, animal models for SARS-CoV-2  vaccine- or drug-development (Service provided by A4 Transgenic mouse  models core facility) | National Core Facility for Biopharmaceuticals
Biotechnology - hACE2 transgenic mouse, animal models for SARS-CoV-2 vaccine- or drug-development (Service provided by A4 Transgenic mouse models core facility) | National Core Facility for Biopharmaceuticals

One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice  from SARS-CoV-2 upper and lower respiratory tract infection | PNAS
One or two injections of MVA-vectored vaccine shields hACE2 transgenic mice from SARS-CoV-2 upper and lower respiratory tract infection | PNAS

Age associated susceptibility to SARS-CoV-2 infection in the K18-hACE2  transgenic mouse model | GeroScience
Age associated susceptibility to SARS-CoV-2 infection in the K18-hACE2 transgenic mouse model | GeroScience

COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic  mice | Human Genomics | Full Text
COVID-19 preclinical models: human angiotensin-converting enzyme 2 transgenic mice | Human Genomics | Full Text

Viruses | Free Full-Text | Virulence Profiles of Wild-Type, P.1 and Delta  SARS-CoV-2 Variants in K18-hACE2 Transgenic Mice
Viruses | Free Full-Text | Virulence Profiles of Wild-Type, P.1 and Delta SARS-CoV-2 Variants in K18-hACE2 Transgenic Mice

A longitudinal molecular and cellular lung atlas of lethal SARS-CoV-2  infection in K18-hACE2 transgenic mice - eBioMedicine
A longitudinal molecular and cellular lung atlas of lethal SARS-CoV-2 infection in K18-hACE2 transgenic mice - eBioMedicine

COVID-19 K18-hACE2 Transgenic Mouse Model - IITRI
COVID-19 K18-hACE2 Transgenic Mouse Model - IITRI

Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5 |  Science Advances
Age-dependent acquisition of pathogenicity by SARS-CoV-2 Omicron BA.5 | Science Advances

Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta  SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice | Journal of  Virology
Evaluating Antibody Mediated Protection against Alpha, Beta, and Delta SARS-CoV-2 Variants of Concern in K18-hACE2 Transgenic Mice | Journal of Virology

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in  K18-hACE2 transgenic mice despite convalescent plasma therapy | bioRxiv
SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy | bioRxiv

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice |  Nature
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice | Nature

Novel transgenic mice with Cre-dependent co-expression of GFP and human  ACE2: a safe tool for study of COVID-19 pathogenesis | Transgenic Research
Novel transgenic mice with Cre-dependent co-expression of GFP and human ACE2: a safe tool for study of COVID-19 pathogenesis | Transgenic Research

SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in  K18-hACE2 transgenic mice despite convalescent plasma therapy | bioRxiv
SARS-CoV-2 B.1.1.7 and B.1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy | bioRxiv

Molecules | Free Full-Text | K18- and CAG-hACE2 Transgenic Mouse Models and  SARS-CoV-2: Implications for Neurodegeneration Research
Molecules | Free Full-Text | K18- and CAG-hACE2 Transgenic Mouse Models and SARS-CoV-2: Implications for Neurodegeneration Research

Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human  Angiotensin-Converting Enzyme 2 - ScienceDirect
Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 - ScienceDirect

Frontiers | Experimental Models of COVID-19
Frontiers | Experimental Models of COVID-19

Transgenic hACE2 mice for SARS-CoV-2 and COVID-19 | Taconic Biosciences
Transgenic hACE2 mice for SARS-CoV-2 and COVID-19 | Taconic Biosciences

SARS-2 protection studies in K18-hACE2 transgenic mice (A) Schematic... |  Download Scientific Diagram
SARS-2 protection studies in K18-hACE2 transgenic mice (A) Schematic... | Download Scientific Diagram

Mouse model of fatal COVID-19 developed for vaccine and drug testing
Mouse model of fatal COVID-19 developed for vaccine and drug testing

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory  responses in K18-hACE2 mice | PLOS ONE
SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice | PLOS ONE

034860 - K18-hACE2 Strain Details
034860 - K18-hACE2 Strain Details

hACE2 transgenic mouse model for coronavirus (COVID-19) research
hACE2 transgenic mouse model for coronavirus (COVID-19) research

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung  inflammation and impaired function | Nature Immunology
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function | Nature Immunology

Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2  transgenic mouse model | Scientific Reports
Efficacy of GC-376 against SARS-CoV-2 virus infection in the K18 hACE2 transgenic mouse model | Scientific Reports